ERCC1 (Autostainer Link 48)
SKU: DO
Supplier: Dako (view all products)
Excision repair cross-complementing rodent repair deficiency-1 (ERCC1) is a ~33 kDa nuclear protein involved in the nucleotide excision repair pathway (NER). The NER pathway is utilized to repair DNA mutations that occur as a result of DNA damage from external compounds, environmental carcinogens and UV-light.
Antibodies to ERCC1 is a useful aid for classification of a variety of tumor types including non-small cell lung carcinoma, gastroesophageal carcinoma, urothelial carcinoma, bladder carcinoma, and head and neck squamous cell carcinoma.