Supplier: Dako (view all products)
Reacts with nucleophosmin (NPM) and its mutated counterpart NPMc. NPM is predominantly localized in the nucleus of cells in most tissues. However, NPMc is aberrantly accumulated in the cytoplasm of leukemic blasts in a large subgroup of acute myeloid leukemia (AML) cases with a normal karyotype (1-2). The antibody may be a useful aid for classification of acute myeloid leukemia (3).