Prostate-Specific Membrane Antigen (Autostainer Link 48)
Supplier: Dako (view all products)
Prostate-specific membrane antigen (PSMA) is expressed in normal and malignant prostatic epithelium and in a subset of non-prostatic tissues. In prostate cancer, PSMA expression has been shown to correlate with disease progression, with highest levels expressed in hormone-refractory and metastatic disease. The cellular localization of PSMA is cytoplasmic and/or membranous.
This antibody labels PSMA-expressing cells in normal and neoplastic tissues and is a useful aid for classification of prostate adenocarcinomas.