Tissue Inhibitor of Metalloproteinases 1 (Concentrate)

SKU: DO
Supplier: Dako (view all products)

Reacts with tissue inhibitor of metalloproteinases 1 (TIMP-1). TIMP-1 is expressed in a proportion of stromal myofibroblast-like cells adjacent to invading cancer cells of colon adenocarcinomas. Results aid in the classification of adenocarcinomas and colon adenomas (1). TIMP-1 is also expressed in neuroendocrine cells (2). TIMP-1 plays a pivotal role in extracellular matrix remodeling, and may affect malignant cell transformation, cell proliferation and apoptosis (3).