ZAP-70* (Autostainer Link 48)
Supplier: Dako (view all products)
Reacts with ZAP-70 expressed in T cells, natural killer cells, pro/pre B cells but not in normal mature B cells. The antibody is a useful aid for classification of a subset of chronic lymphocytic leukemias (CLL). In CLL, ZAP-70 expression is closely associated with an unmutated configuration of the immunoglobulin heavy-chain variable region (IgVH) genes (1).