c-erbB-2 Oncoprotein (Concentrate)

Supplier: Dako (view all products)

A synthetic peptide, coupled to keyhole limpet hemocyanin, has been used for immunization. The peptide represents part of the predicted 185 kDa oncoprotein encoded by ERBB2, also termed HER2 or NEU. The antibody recognizes an epitope on the cytoplasmic part of the cell membrane-bound c-erbB-2 oncoprotein. Overexpression of c-erbB-2 oncoprotein has been found in 25-30% of human breast carcinomas.