LAT Protein (Concentrate)

LAT (linker for activation of T cells) protein appears early in the T-cell development, at the thymocyte stage, and before expression of terminal deoxynucleotidyl transferase (TdT) in embryos. It is expressed by natural killer cells and T cells without restriction to any T-cell subpopulation. Megakaryocytes and mast cells also express LAT protein, whereas other myeloid cells, monocytic derived cells and B cells do not express LAT protein.